منصة الدواء » central nervous system agents » antiemetic/antivertigo agents


📆 الإثنين   2023-12-11

🕘 1:12 PM بتوقيت مكة

 
central nervous system agents
antiemetic/antivertigo agents
Vomiting is controlled by the vomiting center in the medulla. Vomiting center is activated by either one of four trigger zones: chemoreceptor trigger zone, vestibular nuclei, cerebral cortex and gastrointestinal tract. Vomiting center is controlled by serotonin (5-HT3), muscarinic and histamine (H1) receptors.
Chemoreceptor trigger zone is sensitive to chemical stimuli, such as opioids and cytotoxic drugs. It is under the control of dopamine, serotonin (5-HT3) and opioid receptors.
Vestibular nuclei is controlled by muscarinic and histamine (H1) receptors. This is activated in vertigo or motion sickness.

Drug classes:

 

Ⓖ Amisulpride


® Barhemsys

 

Ⓖ Aprepitant


® Cinvanti

 

Ⓖ Aprepitant


® Emend





 
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